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Assisted Conception

From comprehensive fertility-related diagnostics to advanced fertility services, we have the solutions for you no matter what your fertility goals are.

In-Vitro Fertilisation (IVF)

In-Vitro Fertilisation (IVF) is a highly popular assisted conception method. It involves the administration of hormone medication and injections to stimulate the ovaries, leading to the production of a larger number of eggs than usual. While under sedation, the eggs are extracted during a procedure and then fertilized with a sperm sample to create one or more embryos. Finally, the embryos are transferred to the uterus.

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Intrauterine Insemination (IUI)

Intrauterine Insemination (IUI) is a method that supports natural conception by placing specially processed sperm directly into the uterus. This technique enhances the chances of sperm reaching the fallopian tubes and successfully fertilizing the matured egg. In some cases, medication and a trigger injection may be used to stimulate the production of multiple eggs and time their release from the follicles.

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Ovulation Induction

Ovulation Induction is a hormone treatment method that involves oral medications like Clomid or Letrozole. These medications stimulate the ovaries to develop eggs and induce ovulation, increasing the chances of successful conception through timed intercourse. Ovulation Induction can be used in conjunction with IUI or as a primary method, particularly for women with irregular menstrual cycles or those who do not ovulate at all.

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First method

In-Vitro Fertilisation (IVF)

Why In-Vitro Fertilisation?

Commonly referred to as IVF, In-Vitro Fertilisation is a popular assisted conception method whereby hormone medication/injections are taken to stimulate a woman’s ovaries to produce more eggs than normal.

These eggs are extracted and then fertilised with a sperm sample to create embryo(s). The embryo(s) are then transferred to the uterus.

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A standard IVF cycle

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Ovarian Stimulation

You take hormone injections for about 9 to 12 days, and typically will need 2 or 3 transvaginal ultrasound scans to check on follicular development.

Egg Collection

Also called OPU for Oocyte Pick-Up, your fertility specialist will insert a needle attached to a catheter through your vaginal while guided by ultrasound to collect your eggs. This is done while you are sedated/under anaesthesia and takes only about 15 – 20 minutes.

Fertilisation

Your eggs are fertilised by Intracytoplasmic Sperm Injection (ICSI) method using your partner’s sperm, or by using a donor’s sperm.

Embryo Growth

Your embryo(s) are monitored for the next 3 to 6 days and have the option for genetic testing.

Embryo Transfer

This could be a fresh or frozen embryo transfer, your fertility specialist will gently insert a catheter through your cervix to your womb while being guided by ultrasound. Your embryo is then passed through this catheter right to the endometrium lining of your womb. You can opt to increase the chance of implantation of your embryo with a receptivity analysis before undergoing this step.1

Who can benefit from IVF as a treatment option

Women with tubal factors or ovulation disorders

IVF does not require the need or function of our fallopian tubes, bypassing any tubal factors. Even with irregular menses, IVF can still be successful thanks to fertility medications.

Men with impaired sperm production or function

Sperm for fertilisation can be extracted from the source, or even with a donor’s sperm

Same-sex couples

Your fertility goals for family-building can still be met via IVF treatment

Supplementing services to your IVF treatment

Services to help make your IVF a greater success

Egg or sperm donors

An option to consider when you are faced with low quality or diminished egg reserves; or when your sperm is not viable for treatment even when extracted directly from the testicles.

Learn more about Sperm and Egg Donation/Bank/Exchange here

Preimplanation genetic testing

Reduces your risks of miscarriage and genetic abnormalities by screening your embryos before deciding the best embryo(s) to transfer to your womb. PGT is also a strong option for couples who do not want to pass down a known genetic disease that runs in the family to their children.

Learn more about Genetic Testing here

Gestational surrogacy

Enables you to achieve your dream of having a child with the help of another woman who agrees to carry your baby to term.

Learn more about Surrogacy here

MIRA endometrial receptivity test

Tells you the best window of time that your womb is ready to receive your precious embryo(s). This takes place during your preparation for frozen embryo transfer (FET).

Learn more about MIRA here

The great benefits that IVF can offer you

Some control over time

You can choose when to start a family by preserving your fertility until such time that you are ready without the stresses of a ticking biological clock.

Less chances of miscarriage

Known chromosome abnormalities can ultimately cause a miscarriage, and this can be detected with Preimplantation Genetic Testing for Aneuploidy (PGT-A).

Use of donor eggs or sperm

You can still have a baby even if you are unable to produce eggs or sperm

Not passing down a genetic disease

Together with Preimplantation Genetic Testing for Monogenic disease (PGT-M), your embryos can be tested for a disease that you carry in your genes before transferring the ones that are free of that disease

Second method

Intrauterine Insemination (IUI)

Why Intrauterine Insemination?

Often an early option of trying to conceive method, IUI basically helps nature along the way by introducing more viable, healthy sperms to find the egg at the right time… therefore increasing the chance of conceiving.

Before opting for IUI however, your fertility specialist might need you to undergo a diagnostic test called hysterosalpingogram (HSG) to rule out any blockage/growth abnormalities that could render your IUI treatment futile. A safe medical grade dye is injected into the cavity of uterus and womb, and observed via x-ray or sonogram to determine if your fallopian tubes are open/unblocked and your uterus appear to be normal.

With your uterus and fallopian tubes in normal conditions, only then can the concentrated sperm injected in during IUI procedure could travel from the uterus and to the tubes to meet your mature egg making its way down.

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Who can consider having IUI

Couples with
unexplained infertility

Both you and your partner checked out alright with relatively normal results of your fertility assessments, but still not getting pregnant.

Women with ovulation disorders

Even if you have irregular menses, IUI can still be a first line of option for your to try to conceive.

Men with blocked reproductive ducts

You can still attempt IUI with sperm extracted from the testicles, or by using a sample from a sperm donor.

Single females or same-sex couples

When you opt for a sperm donor for family-building goals.

Third method

Ovulation Induction (OI)

Often an early option of trying to conceive method, IUI basically helps nature along the way by introducing more viable, healthy sperms to find the egg at the right time… therefore increasing the chance of conceiving.

Before opting for IUI however, your fertility specialist might need you to undergo a diagnostic test called hysterosalpingogram (HSG) to rule out any blockage/growth abnormalities that could render your IUI treatment futile. A safe medical grade dye is injected into the cavity of uterus and womb, and observed via x-ray or sonogram to determine if your fallopian tubes are open/unblocked and your uterus appear to be normal.

With your uterus and fallopian tubes in normal conditions, only then can the concentrated sperm injected in during IUI procedure could travel from the uterus and to the tubes to meet your mature egg making its way down.

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FAQs

How long does it take for sperm to reach the egg in IUI?

About half an hour, give and take, but that will depend if your egg has been released and making its way down your fallopian tube. Otherwise, washed sperm could live up to 72 hours inside you and wait for the egg when you ovulate.

What’s the success rate for IUI?

Across many reports and medical journals, the rate of success per cycle can be anywhere between 7% to 25% due to a number of factors. The success rate decreases with a woman’s age due to egg quality factor, assuming she has 2 healthy fallopian tubes and without pre-existing conditions such as endometriosis. The quality of the sperm sample for this procedure is also another contributing factor to IUI success

Can twin pregnancies happen with Ovulation Induction?

The risk of multiple pregnancy can happen when fertility medications are used during an ovulatory cycle, but monitoring scans and dosage management by your fertility specialist with the objective of yielding a single mature egg release can reduce the chances of twin/triplet pregnancies.

How long is the entire IVF process?

If your IVF cycle involves a fresh embryo transfer, it can end in 1 month from the time you start your follicular stimulating hormone (FSH) injections. If you are opting for Genetic Testing it would take another 2 weeks from the time your embryos are biopsied and sent for testing. Once the results are out, you would need another 3 to 6 weeks to prepare for your frozen embryo transfer. These indications of time still depends on your body’s responses to medication during the treatment process, which may shorten or lengthen the duration by a few days or a week at most.

Any side effects from IVF treatment?

Hormonal medications and injections that you take during IVF process with the purposes of getting your body to produce more eggs than it normally would could cause some effects such as mild headaches, hot flushes, mood swings, fatigue or the feeling of bloatedness. In rare cases, ovarian hyper stimulation syndrome (OHSS) can occur when the ovaries over-respond to the injectable hormones.

What’s the success rate for IVF?

Couples tend to ask fertility clinics about their success rates and many clinics report their successes differently. In truth, the individual factors of each couple is extremely important for an IVF treatment to be successful. This is because your fertility state and medical condition is different from another person’s. What we do know with worldwide reports and in general across all women of all ages and factors is that, 1 in 2 couples can get pregnant with conventional IVF. The odds of success is even higher now with great fertility techs such as genetic testing and MIRA, reporting up to 85% of success in certain groups of patients.

Not ready for IVF or IUI right now?

Here are some great, practical options for you to consider doing now for your future fertility

Save your eggs for later

Freezing your eggs now would mean that they retain the quality and quantity you have now, and use them in later years.

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Freeze your sperm

Save samples of your swimmers if your work or hobby can be physically hazardous; or if you have a medical decision to make that could potentially hamper you from fathering children.

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Keep tissues of your ovary

A modern option if you are facing a health hurdle now that could jeopardize your fertility in the long run.

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